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Wellness

Right drug. Right dose. Right patient.
Presented by a 608today Partner
a man smiles for a camera with a science lab behind him
“I want to make discoveries so we can better understand how diseases happen and how we can prevent them and treat them,” Hebbring said. | Photo provided by All of Us
Ask Scott J. Hebbring to explain what in the world pharmacogenomics is and watch his eyes light up like a child’s. That’s because the top principal investigator for All of Us Research Program Wisconsin grew up with a wide-eyed fascination with what makes people, and things, tick.

“While other kids were out playing sports, I was home watching Mr. Wizard’s World,” said Hebbring, who earned a Ph.D. in biochemistry and molecular biology. “I was that kid in the backyard turning over rocks to see what’s lurking beneath. As I grew older, I was more interested in turning over the more metaphorical rocks, which is what science is about now.”

The 4-1-1 on pharmacogenomics

The research scientist for the Center for Precision Medicine Research at Marshfield Clinic Research Institute hopes others may be equally intrigued by how medicine interacts with our inherited genes. That’s pharmacogenomics, plain and simple.

Pharmacogenomics is a non-invasive test that tells your doctors what DNA markers you have and can help rule in and rule out medications. It can not only impact the type of drug to prescribe, but pharmacogenomics may help your physician prescribe the right dose. It can even help avoid side effects of medications.

“Roughly 80% of the population at some point will take one or more medications that may be impacted by the genetics they inherited,” Hebbring explains. “And oftentimes these medications may be contraindicated based on their genetics.”

Knowing how your body interacts with certain medications is just one complimentary report given to participants in All of Us — an ambitious effort to gather health data from one million+ people living in the country to accelerate research that may improve health.

Keep reading to learn how the groundbreaking research is helping participants better understand their genes and what that means for their overall health and wellness.
It's all in the genes
Asked

Have you ever had genetic testing?
A. Yes, I’ve done a DNA test to find out more about my ancestry.
B. Yes, I’ve done testing related to having a child.
C. Yes, I’ve been tested to assess my risk for certain diseases.
D. Yes, I’ve done DNA testing for one or more of the above reasons.
E. No, I’ve never done any genetic testing.
We're curious
Events
Tuesday, March 26
  • Queer Cribbage Club | Tuesday, March 26 | 6-8 p.m. | Delta Beer Lab, 167 E. Badger Rd., Madison | Cost of purchase | Opponents typically rotate to play three games a night, with bragging rights to the high scorer of the evening.
Wednesday, March 27
  • Open Jam | Wednesday, March 27 | 6-9 p.m. | The Rigby, 119 E. Main St., Madison | Free | Stop by to enjoy the music, or bring an instrument to jam.
  • Taylor Swift Music Bingo | Wednesday, March 27 | 7-8 p.m. | Sencha Tea Bar, 224 State St., Madison | $10 | Swiftly make your way for a night of musical bingo with fellow Swifties.
Thursday, March 28
  • Application Assistance | Thursday, March 28 | 11 a.m.-2 p.m. | Goodman South Madison Library, 2222 S. Park St., Madison | Free | Get help navigating application processes and filling out forms required for housing, health, and other community support services.
  • Kyle Kinane | Thursday, March 28 | Comedy on State, 202 State St., Madison | $30-$40 | See a set from this comedian who has worked on “The Tonight Show” and “Conan.”
Friday, March 29
  • Interactive Trash Lab | Friday, March 29 | 10 a.m.-12 p.m. | Monona Public Library, 1000 Nichols Rd., Madison | Free | Kids can learn about the implications of waste, enjoy a snack in the story room, and check out some books.
  • Laptop Fridays | Friday, March 29 | 12-3 p.m. | Karben4, 3698 Kinsman Blvd., Madison | Cost of purchase | Bring your computer to do some work and enjoy $4 pints.
Saturday, March 30
  • Spring Eggstravaganza | Saturday, March 30 | 9 a.m.-12 p.m. | Hometown USA Festival Park, 111 Lincoln St., Verona | Free | Children will get the opportunity to hunt for Easter eggs, pet a potbellied pig, make crafts, race in a potato sack, and more.
  • UScellular Parking Lot Party | Saturday, March 30 | 11 a.m.-3 p.m. | UScellular Madison East, 4722 E. Towne Blvd., Madison | Free | Enjoy free sips from North Village Coffee, meet 106.3 FM DJs, and win raffle prizes (selfie lights will be given to the first 100 attendees).
Events calendar here
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News Notes
Development
  • With the new Wisconsin History Center facility breaking ground, there’s an opportunity to redesign the adjacent plaza space at the top of State Street. The city is welcoming input on Wednesday, April 3, from 5:30 to 6:30 p.m. at 30 N. Carroll St.
Arts
  • Baraboo’s historic Al. Ringling Theatre is being acquired by the Wisconsin Historical Society (WHS) after raising $3 million from donors. The ornate building will host performances and community events as an extension of Baraboo’s Circus World, also run by WHS. (Wisconsin Public Radio)
State
  • The Wisconsin DMV is reminding people about valid IDs for the Tuesday, April 2 primary. Voters must show ID, but there’s no separate “Voter ID” requirement. To obtain a free ID, start online or call the toll-free hotline at (844) 588-1069. Wisconsinites can check online if their ID will be accepted at polls. (NBC 15)
Closing
  • Indian Lake County Park will close for Hwy 19 construction starting Monday, April 22. Park users have “local access” to main and dog/lake parking lots until April 21, 2024. The park will be closed for 30 days to install a pedestrian underpass linking it to Halfway Prairie Wildlife Area.
Outdoors
  • The Wisconsin DNR seeks input on its elk management plan. There will be in-person forums in Black River Falls (April 3) and Hayward (April 4), and a Zoom meeting on Wednesday, April 10, from 6:30 to 8:30 p.m. Register now.
Edu
  • One Community Bank is hosting a teen financial literacy workshop on Wednesday, April 17. The workshop, to take place at 1565 Landmark Dr. in Cottage Grove, will discuss budgeting, accounting, credit scores, and more. Registration is required and seating is limited.
Family
  • PBS Wisconsin is inviting families to an open house of the studio. Taking place on Saturday, April 6, from 10 a.m. to 4 p.m. in Vilas Hall (821 University Ave.), the festivities will include behind-the-scenes peeks, special screenings, character appearances, and tours.
Award
  • What keeps Oregon resident Dan Bertler running is, well, running. Bertler completed all six World Marathon Majors. That means, he’s run the Boston, Chicago, London, Berlin, New York City, and Tokyo marathons. “You can start running any time you want,” he said. “It’s one foot in front of the other.” (WMTV)
Sports
  • Badgers men’s basketball favorite Connor Essegian is no longer a Badger. After a stellar freshman season, and a diminished role on the court during his sophomore season, Essegian announced his intent to enter the transfer portal. He said, “I would like to say thank you Badger Nation for everything.”
Plan Ahead
  • Psst — Taxes are almost due. Use E-file for quick, online filing. Plus, file your federal taxes for free with their basic software plan.*
 
Arts

🎭 Looking forward to Forward Theater

Forward Theater announces its season 16 lineup
The Overture Center at night lit up from the inside with rainbow lights
Forward Theater performances take place at the Overture Center. | Photo by Overture Center
The Forward Theater Company announced its season 16 lineup. The season’s theme, “Through Thick and Thin,” encapsulates the intricacies of relationships — family, friendship, and love.

Shows will run from September of 2024 through April 2025 at the Overture Center. Season tickets range from $120-$400.

King James | Sept. 12-29
This fast-paced comedy celebrating LeBron James’ impact on Cleveland explores loyalty, legacy, and the connection between two die-hard fans.

Murder Girl | Nov. 7-24
Set in a Wisconsin supper club, this lighthearted story centers around found family. Twins struggle to run their family business amidst a murderous subplot.

Summer, 1976 | Jan. 30-Feb. 16
During a bicentennial summer in Ohio, Diana and Alice become close friends while sharing their experiences being mothers and wives.

A Case for the Existence of God | March 27-April 13
Two men in Idaho forge a profound bond while discovering the meaning of life among other things like loan terms, family life, and personal dreams.
The Buy
The Avryn & Co. wristlet sets. Bop around with all of your essentials and look stylish doing it.
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The Wrap
 
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Today’s edition by:
Ally
From the editor
It’s the final week of our 608today Pizza Bracket competition, and you guys have three days left to place your votes. Ian’s or Salvatore’s? You decide.
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